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- Villa A et al. <\/em>An update on pharmacotherapies in active development for the management of cancer regimen-associated oral mucositis. Expert Opinion Pharmacother 2020. Elad S et al. MASCC\/ISOO Clinical Practice Guidelines for the Management of Mucositis Secondary to Cancer Therapy. <\/span><\/em>Cancer 2020.<\/em><\/li>\n<\/ul>\n
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The indications and medical needs are well defined, with no known barriers to diagnosis and treatment: patients receiving chemotherapy or radiotherapy known to be mucitogenic should receive preventive treatment for oral mucositis.<\/p>\n
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Undergoing oncology treatment suffering from oral mucositis \/ candidiasis: CH = 32,700; EU-5 = 772,000 patients.<\/p>\n
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Despite its frequency and impact, the therapeutic options for mucositis are still limited: sodium bicarbonate solution<\/span> (most commonly used), triazoles, amphotericin B, KGF-1, Photobiomodulation, benzydamine. These available therapeutic options have questionable efficacy vs.<\/i> cost and\/or tolerability profiles and none is currently recognized as standard of care.<\/p>\n
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Oral mucositis: common side effect of cancer treatments<\/h2>\n
Oral mucositis is a common adverse effect of cytotoxic cancer treatments. It remains one of the most painful and disruptive adverse effects of chemotherapy and radiotherapy. Despite its frequency and impact, preventive or therapeutic options remain limited. These available therapeutic options have questionable efficacy vs. cost and\/or tolerability profiles and none is currently recognized as standard of care.<\/p>\n
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- (Upper image) Large ulceration of the lower labial mucosa of a patient receiving deforolimus (AP23573) is shown. The borders were irregular. Although the ulcer was not penetrating, it was extremely painful. The clinical appearance was identical to that of major aphthous stomatitis.<\/em><\/li>\n<\/ul>\n
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- Oral candidiasis, 51-year-old female, after the 18th fraction of radiotherapy in the OPC group. Whitish pseudomembranes and drops (arrows) are observed on the hard palate, which is devoid of mucositis (A). (A). Mucositis grade 2 to 3, 57-year-old male, after the 25th fraction of radiotherapy in the non-OPC group. Whitish pseudomembranes and drops (arrows) are observed on the hard palate, which is devoid of mucositis (A). (B). (OPC: oropharyngeal candidiasis)<\/em><\/li>\n<\/ul>\n
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- (Picture 1 – mouth) – Sonis S et al. Preliminary characterization of oral lesions associated with inhibitors of mammalian target of rapamycin in cancer patients. Cancer 2010<\/em><\/li>\n<\/ul>\n
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- \n
- (Pictures 2 & 3 – esophagus) – Qiu WZ et al. A retrospective study of 606 cases of nasopharyngeal carcinoma with or without oropharyngeal candidiasis during radiotherapy. PLOS one 2017<\/em><\/li>\n<\/ul>\n
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- \n
- (Upper image) Large ulceration of the lower labial mucosa of a patient receiving deforolimus (AP23573) is shown. The borders were irregular. Although the ulcer was not penetrating, it was extremely painful. The clinical appearance was identical to that of major aphthous stomatitis.<\/em><\/li>\n<\/ul>\n
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Oral mucositis: common side effect of cancer treatments<\/h2>\n
Oral mucositis is a common adverse effect of cytotoxic cancer treatments. It remains one of the most painful and disruptive adverse effects of chemotherapy and radiotherapy. Despite its frequency and impact, preventive or therapeutic options remain limited. These available therapeutic options have questionable efficacy vs. cost and\/or tolerability profiles and none is currently recognized as standard of care.<\/p>\n
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- \n
- (Upper image) Large ulceration of the lower labial mucosa of a patient receiving deforolimus (AP23573) is shown. The borders were irregular. Although the ulcer was not penetrating, it was extremely painful. The clinical appearance was identical to that of major aphthous stomatitis.<\/em><\/li>\n<\/ul>\n
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- \n
- Oral candidiasis, 51-year-old female, after the 18th fraction of radiotherapy in the OPC group. Whitish pseudomembranes and drops (arrows) are observed on the hard palate, which is devoid of mucositis (A). (A). Mucositis grade 2 to 3, 57-year-old male, after the 25th fraction of radiotherapy in the non-OPC group. Whitish pseudomembranes and drops (arrows) are observed on the hard palate, which is devoid of mucositis (A). (B). (OPC: oropharyngeal candidiasis)<\/em><\/li>\n<\/ul>\n
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Platform of galenic solutions<\/h2>\n
Answers to a proven medical need to reduce the side adverse effects of chemo and radiotherapy (inflammation, mucositis, oral candidiasis) using scientifically validated natural phytotherapeutic and probiotic products, that have been scientifically validated.<\/p>\n
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image_icon_background_color__sticky_enabled=”#7EBEC5″ image_icon_background_color__sticky=”#7EBEC5″]<\/p>\n
- \n
- Oral Topical Therapy \/ Mouth spray \/ Mouth gel<\/li>\n
- Developed galenic pre-formulas<\/li>\n
- Organic plants grown in Switzerland, in particular the willowherb, a cultivar developed over 3 years, rich in flavonoids and oenotheins A and B, resistant and fast growing<\/li>\n
- Clinical safety and skin compatibility tested<\/li>\n
- Microbiological stability tested (28 days)<\/li>\n
- Preliminary proof of efficacy in oncology<\/li>\n<\/ul>\n
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- \n
- Existing base formula<\/li>\n
- Adaptable formula for worldwide exclusivity<\/li>\n
- Available clinical studies<\/li>\n<\/ul>\n
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Cultures of organic Epilobium lanceolatum in Valais<\/h2>\n
The small-flowered willowherb, from the Onagraceae family, is used in traditional medicine for its antioxidant, antimicrobial and anti-inflammatory properties. Over the course of several years, we have selected a cultivar and developed an extraction process that allows us to obtain an extract particularly rich in Oenothein B, an active ingredient at the origin of the IBEX Tx innovation because of its anti-adhesion activity against C. albicans. The small-flowered willowherb used in IBEX Tx is grown in the Swiss Alps according to the principles of organic farming.<\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row disabled_on=”off|on|on” _builder_version=”4.17.4″ _module_preset=”default” locked=”off” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” border_radii=”off||||” global_colors_info=”{}”][et_pb_text content_tablet=”<\/p>\n
Cultures of organic Epilobium lanceolatum in Valais<\/h2>\n
The small-flowered willowherb, from the Onagraceae family, is used in traditional medicine for its antioxidant, antimicrobial and anti-inflammatory properties. Over the course of several years, we have selected a cultivar and developed an extraction process that allows us to obtain an extract particularly rich in Oenothein B, an active ingredient at the origin of the IBEX Tx innovation because of its anti-adhesion activity against C. albicans. The small-flowered willowherb used in IBEX Tx is grown in the Swiss Alps according to the principles of organic farming.<\/p>\n
” content_phone=”<\/p>\n
Cultures of organic Epilobium lanceolatum in Valais<\/h2>\n
The small-flowered willowherb, from the Onagraceae family, is used in traditional medicine for its antioxidant, antimicrobial and anti-inflammatory properties. Over the course of several years, we have selected a cultivar and developed an extraction process that allows us to obtain an extract particularly rich in Oenothein B, an active ingredient at the origin of the IBEX Tx innovation because of its anti-adhesion activity against C. albicans. The small-flowered willowherb used in IBEX Tx is grown in the Swiss Alps according to the principles of organic farming.<\/p>\n
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Cultures of organic Epilobium lanceolatum in Valais<\/h2>\n
The small-flowered willowherb, from the Onagraceae family, is used in traditional medicine for its antioxidant, antimicrobial and anti-inflammatory properties. Over the course of several years, we have selected a cultivar and developed an extraction process that allows us to obtain an extract particularly rich in Oenothein B, an active ingredient at the origin of the IBEX Tx innovation because of its anti-adhesion activity against C. albicans. The small-flowered willowherb used in IBEX Tx is grown in the Swiss Alps according to the principles of organic farming.[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_3,1_3,1_3″ custom_padding_last_edited=”on|desktop” module_class=”tablet-three-cols” _builder_version=”4.17.4″ _module_preset=”default” custom_margin_tablet=”||0px||false|false” custom_margin_phone=”||0px||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”||35px||false|false” custom_padding_tablet=”||35px||false|false” custom_padding_phone=”||0px||false|false” animation_style=”fold” animation_direction=”bottom” scroll_fade=”0|80|80|100|60%|100%|100%” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”4.16″ _module_preset=”default” border_radii=”off|50px||50px|” global_colors_info=”{}”][et_pb_image src=”https:\/\/ibextx.ch\/wp-content\/uploads\/2022\/03\/Nos-cultures-dEpilobium-parviflorum-BIO-en-Valais-Nos-cultures-dEpilobium-parviflorum-BIO-en-Valais.jpg” alt=”Cultures of organic Epilobium parviflorum in Valais” title_text=”Cultures of organic Epilobium parviflorum in Valais” _builder_version=”4.17.4″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.16″ _module_preset=”default” border_radii=”off|50px||50px|” global_colors_info=”{}”][et_pb_image src=”https:\/\/ibextx.ch\/wp-content\/uploads\/2022\/03\/Nos-cultures-dEpilobium-parviflorum-BIO-en-Valais-3.jpg” title_text=”Our organic Epilobium parviflorum crops in Valais 3″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.16″ _module_preset=”default” border_radii=”off|50px||50px|” global_colors_info=”{}”][et_pb_image src=”https:\/\/ibextx.ch\/wp-content\/uploads\/2022\/03\/Nos-cultures-dEpilobium-parviflorum-BIO-en-Valais-2.jpg” title_text=”Our organic Epilobium parviflorum crops in Valais 2″ _builder_version=”4.16″ _module_preset=”default” filter_saturate=”120%” filter_brightness=”109%” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_3,1_3,1_3″ custom_padding_last_edited=”on|tablet” disabled_on=”on|on|on” module_class=”tablet-three-cols” _builder_version=”4.17.4″ custom_margin=”0px||||false|false” custom_margin_tablet=”0px||||false|false” custom_margin_phone=”0px||||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”0px||||false|false” custom_padding_tablet=”0px||||false|false” custom_padding_phone=”0px||||false|false” disabled=”on” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”4.16″ border_radii=”off||||” global_colors_info=”{}”][et_pb_number_counter number=”4″ percent_sign=”off” disabled_on=”on|on|on” _builder_version=”4.16″ number_font=”Numans|700|||||||” number_text_color=”#484749″ number_font_size=”60px” number_line_height=”1em” custom_margin_tablet=”0px||0px||false|false” custom_margin_phone=”0px||0px||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”0px||0px||false|false” number_font_size_tablet=”35px” number_font_size_phone=”25px” number_font_size_last_edited=”on|phone” number_line_height_tablet=”2em” number_line_height_phone=”4em” number_line_height_last_edited=”on|tablet” disabled=”on” global_colors_info=”{}”][\/et_pb_number_counter][et_pb_text disabled_on=”on|on|on” _builder_version=”4.16″ text_font=”Work Sans|||on|||||” text_font_size=”1.2vw” text_letter_spacing=”2px” text_line_height=”1.2em” header_2_font_size=”2.5vw” background_color=”rgba(34,42,137,0.09)” text_orientation=”center” custom_padding=”25px|20px|25px|20px|true|true” custom_padding_tablet=”33px|5px|33px|5px|true|true” custom_padding_phone=”|12px||12px|true|true” custom_padding_last_edited=”on|tablet” text_font_size_tablet=”2.3vw” text_font_size_phone=”4.3vw” header_2_font_size_tablet=”5vw” header_2_font_size_phone=”9vw” header_2_font_size_last_edited=”on|phone” border_radii=”off|20px||20px|” border_radii_tablet=”off|25px||25px|” border_radii_phone=”off|25px||25px|” border_radii_last_edited=”on|phone” global_colors_info=”{}” text_font_size__hover=”14px” text_font_size__hover_enabled=”14px”]<\/p>\n
Plots<\/p>\n
\n<\/div>\n<\/div>\n[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.16″ border_radii=”off||||” global_colors_info=”{}”][et_pb_number_counter number=”1200″ percent_sign=”off” disabled_on=”on|on|on” _builder_version=”4.16″ number_font=”Numans|700|||||||” number_text_color=”#484749″ number_font_size=”60px” number_line_height=”1em” custom_margin_tablet=”0px||0px||false|false” custom_margin_phone=”0px||0px||false|false” custom_margin_last_edited=”on|tablet” custom_padding=”0px||0px||false|false” number_font_size_tablet=”35px” number_font_size_phone=”25px” number_font_size_last_edited=”on|phone” number_line_height_tablet=”2em” number_line_height_phone=”4em” number_line_height_last_edited=”on|tablet” global_colors_info=”{}”][\/et_pb_number_counter][et_pb_text disabled_on=”on|on|on” _builder_version=”4.16″ text_font=”Work Sans|||on|||||” text_font_size=”1.2vw” text_letter_spacing=”2px” text_line_height=”1.2em” header_2_font_size=”2.5vw” background_color=”rgba(34,42,137,0.09)” text_orientation=”center” custom_padding=”25px|20px|25px|20px|true|true” custom_padding_tablet=”33px|5px|33px|5px|true|true” custom_padding_phone=”|12px||12px|true|true” custom_padding_last_edited=”on|tablet” text_font_size_tablet=”2.3vw” text_font_size_phone=”4.3vw” header_2_font_size_tablet=”5vw” header_2_font_size_phone=”9vw” header_2_font_size_last_edited=”on|phone” border_radii=”off|20px||20px|” border_radii_tablet=”off|25px||25px|” border_radii_phone=”off|25px||25px|” border_radii_last_edited=”on|phone” global_colors_info=”{}” text_font_size__hover=”14px” text_font_size__hover_enabled=”14px”]<\/p>\n
Surface area in m2<\/p>\n
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custom_padding=”15px|9px|15px|9px|true|true” custom_padding_tablet=”15px|5px|15px|5px|true|true” custom_padding_phone=”15px|9px|15px|9px|true|true” custom_padding_last_edited=”on|phone” text_font_size_tablet=”2.3vw” text_font_size_phone=”4.3vw” header_2_font_size_tablet=”5vw” header_2_font_size_phone=”9vw” header_2_font_size_last_edited=”on|phone” border_radii=”off|20px||20px|” border_radii_tablet=”off|25px||25px|” border_radii_phone=”off|25px||25px|” border_radii_last_edited=”on|phone” global_colors_info=”{}” text_font_size__hover=”14px” text_font_size__hover_enabled=”14px”]concentration in active principles[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ use_custom_gutter=”on” gutter_width=”1″ specialty=”on” padding_top_2=”8%” padding_right_2=”15vw” padding_left_2=”100px” padding_top_bottom_link_1=”false” padding_top_bottom_link_2=”false” padding_left_right_link_1=”false” padding_left_right_link_2=”false” disabled_on=”on|off|off” 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About<\/h2>\n
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- IBEX Therapeutics, a Swiss company specialised in therapies based on biological products derived from plant extracts.<\/li>\n<\/ul>\n
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- Founded in 2021 by 4 co-founders with solid experience in the pharmaceutical industry.<\/li>\n<\/ul>\n
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- \n
- Sister company of PHARMALP SA used to create an opportunity to leverage a patent by investing in the development of a pharmaceutical product<\/li>\n<\/ul>\n
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- \n
- Mission: To bring the first product to market within 3 years with a solid proof of concept.<\/li>\n<\/ul>\n
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The company<\/h2>\n
[\/et_pb_text][et_pb_blurb title=”Sister company of PHARMALP SA used to create an opportunity to leverage a patent by investing in the development of a pharmaceutical product.” use_icon=”on” font_icon=”Z||divi||400″ icon_color=”#90BF2A” image_icon_background_color=”rgba(255,255,255,0.24)” icon_placement=”left” image_icon_width=”2.5vw” content_max_width=”100%” _builder_version=”4.27.4″ _module_preset=”default” header_level=”h3″ header_font=”Lato||||||||” header_text_color=”#636373″ header_font_size=”1.3vw” header_line_height=”1.4em” body_font=”Lato||||||||” body_font_size=”1.3vw” body_line_height=”1.8em” image_icon_custom_padding=”8px|8px|8px|8px|false|false” background_layout=”dark” custom_padding=”5px||5px||true” animation_style=”slide” animation_direction=”right” animation=”off” header_font_size_tablet=”16px” header_font_size_phone=”4vw” header_font_size_last_edited=”on|tablet” body_font_tablet=”Lato||||||||” body_font_phone=”Lato||||||||” body_font_last_edited=”on|desktop” 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The company<\/h2>\n
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About<\/h2>\n
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- \n
- IBEX Therapeutics, a Swiss company specialised in therapies based on biological products derived from plant extracts.<\/li>\n<\/ul>\n
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- \n
- Founded in 2021 by 4 co-founders with solid experience in the pharmaceutical industry.<\/li>\n<\/ul>\n
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- \n
- Sister company of PHARMALP SA used to create an opportunity to leverage a patent by investing in the development of a pharmaceutical product<\/li>\n<\/ul>\n
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- \n
- Mission: To bring the first product to market within 3 years with a solid proof of concept.<\/li>\n<\/ul>\n
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- \n
- Values: 2 to 3 values to be discussed together.<\/li>\n<\/ul>\n
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The Ibex Therapeutics team<\/h2>\n
Board of Directors<\/h3>\n
Multidisciplinary team with expertise in the key areas of development (technical, medical, regulatory and commercial).<\/p>\n
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The Ibex Therapeutics team<\/h2>\n
Board of Directors<\/h3>\n
Multidisciplinary team with expertise in the key areas of development (technical, medical, regulatory and commercial).<\/p>\n
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The Ibex Therapeutics team<\/h2>\n
Board of Directors<\/h3>\n
Multidisciplinary team with expertise in the key areas of development (technical, medical, regulatory and commercial).<\/p>\n
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\n\n![\"\"](\"https:\/\/ibextx.ch\/wp-content\/uploads\/2022\/04\/Equipe-Ibex.jpg\")
<\/p>\n Board of Directors<\/h2>\n
(from left to right): Philippe Meuwly – Alain Rinaldi – Pierre Morgon – Alain Merkli<\/p>\n<\/figcaption><\/figure>\n<\/div>\n<\/div>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row disabled_on=”off|on|on” _builder_version=”4.16″ _module_preset=”default” width=”75%” module_alignment=”center” custom_margin=”|||140px|false|false” custom_padding=”|||0px|false|false” global_colors_info=”{}”][et_pb_column type=”4_4″ module_class=”tablet-two-cols” disabled_on=”off|off|off” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text content_tablet=”<\/p>\n
The Ibex Therapeutics team<\/h2>\n
Board of Directors<\/h3>\n
Multidisciplinary team with expertise in the key areas of development (technical, medical, regulatory and commercial).<\/p>\n
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The Ibex Therapeutics team<\/h2>\n
Board of Directors<\/h3>\n
Multidisciplinary team with expertise in the key areas of development (technical, medical, regulatory and commercial).<\/p>\n
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\n\n<\/p>\n Board of Directors<\/h2>\n
(from left to right): Philippe Meuwly – Alain Rinaldi – Pierre Morgon – Alain Merkli<\/p>\n<\/figcaption><\/figure>\n<\/div>\n<\/div>\n
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box_shadow_color__hover_enabled=”on”]<\/p>\n
Partners<\/h2>\n
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Phytotherapeutic range<\/h4>\n
- \n
- Mediplant
https:\/\/mediplant.ch\/index.php\/fr<\/a><\/li>\n<\/ul>\n[\/et_pb_text][et_pb_text _builder_version=”4.21.0″ text_text_color=”#636373″ text_font_size=”1.2vw” text_line_height=”1.8em” header_2_text_color=”#636373″ header_2_font_size=”2.5vw” header_3_font=”Work Sans|600|||||||” header_3_font_size=”18px” header_3_line_height=”1.4em” header_4_font=”Work Sans|600|||||||” header_4_text_color=”#636373″ header_4_font_size=”1.4vw” header_4_line_height=”1.4em” background_layout=”dark” custom_margin=”||0px||false|false” custom_margin_tablet=”||30px” custom_margin_phone=”||30px” custom_margin_last_edited=”off|phone” custom_padding=”0px|0px|0px|0px|true|true” link_option_url=”#” text_font_size_tablet=”2.3vw” text_font_size_phone=”4.3vw” header_2_font_size_tablet=”5vw” header_2_font_size_phone=”9vw” header_2_font_size_last_edited=”on|phone” header_4_font_size_tablet=”22px” header_4_font_size_phone=”20px” header_4_font_size_last_edited=”on|phone” border_radii=”on|10px|10px|10px|10px” box_shadow_style=”preset3″ box_shadow_blur=”0px” box_shadow_color=”rgba(0,0,0,0)” locked=”off” global_colors_info=”{}” text_line_height__hover=”1.7em” text_line_height__hover_enabled=”1.7em” box_shadow_blur__hover=”38px” box_shadow_blur__hover_enabled=”on” box_shadow_color__hover=”rgba(34,42,137,0.09)” box_shadow_color__hover_enabled=”on” text_font_size__hover=”14px” text_font_size__hover_enabled=”14px” text_letter_spacing__hover=”0px” text_letter_spacing__hover_enabled=”0px” text_text_shadow_color__hover=”rgba(0,0,0,0.4)” text_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” link_font_size__hover=”14px” link_font_size__hover_enabled=”14px” link_letter_spacing__hover=”0px” link_letter_spacing__hover_enabled=”0px” link_line_height__hover=”1em” link_line_height__hover_enabled=”1em” link_text_shadow_color__hover=”rgba(0,0,0,0.4)” link_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” ul_font_size__hover=”14px” ul_font_size__hover_enabled=”14px” ul_letter_spacing__hover=”0px” ul_letter_spacing__hover_enabled=”0px” ul_line_height__hover=”1em” ul_line_height__hover_enabled=”1em” ul_text_shadow_color__hover=”rgba(0,0,0,0.4)” ul_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” ol_font_size__hover=”14px” ol_font_size__hover_enabled=”14px” ol_letter_spacing__hover=”0px” ol_letter_spacing__hover_enabled=”0px” ol_line_height__hover=”1em” ol_line_height__hover_enabled=”1em” ol_text_shadow_color__hover=”rgba(0,0,0,0.4)” ol_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” quote_font_size__hover=”14px” quote_font_size__hover_enabled=”14px” quote_letter_spacing__hover=”0px” quote_letter_spacing__hover_enabled=”0px” quote_line_height__hover=”1em” quote_line_height__hover_enabled=”1em” quote_text_shadow_color__hover=”rgba(0,0,0,0.4)” quote_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” background_layout__hover=”light” background_layout__hover_enabled=”light”]<\/p>\n
Production finished product<\/h4>\n
- \n
- Produits dentaires SA<\/li>\n
https:\/\/pd-dental.com<\/a><\/ul>\n
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Probiotic range<\/h4>\n
- \n
- Rosell-Lallemand https:\/\/www.lallemandpharma.com<\/a><\/li>\n<\/ul>\n
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Pharmaceutical development<\/h4>\n
- \n
- Universit\u00e9 de Gen\u00e8ve https:\/\/ispso.unige.ch\/ispso\/index.php<\/a><\/li>\n<\/ul>\n
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Partners<\/h2>\n
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Phytotherapeutic range<\/h4>\n
- \n
- Mediplant
\nhttps:\/\/mediplant.ch\/index.php\/fr<\/a><\/li>\n<\/ul>\n[\/et_pb_text][et_pb_text _builder_version=”4.21.0″ text_text_color=”#636373″ text_font_size=”1.2vw” text_line_height=”1.8em” header_2_text_color=”#636373″ header_2_font_size=”2.5vw” header_3_font=”Work Sans|600|||||||” header_3_font_size=”18px” header_3_line_height=”1.4em” header_4_font=”Work Sans|600|||||||” header_4_text_color=”#636373″ header_4_font_size=”22px” header_4_line_height=”1.4em” background_layout=”dark” custom_margin=”20px||||false|false” custom_margin_tablet=”0px||||false|false” custom_margin_phone=”||30px|3px|false|false” custom_margin_last_edited=”on|desktop” custom_padding=”0px|2px|0px|2px|true|true” link_option_url=”#” header_2_font_size_tablet=”5vw” header_2_font_size_phone=”9vw” header_2_font_size_last_edited=”on|phone” header_4_font_size_tablet=”22px” header_4_font_size_phone=”20px” header_4_font_size_last_edited=”on|phone” border_radii=”on|10px|10px|10px|10px” box_shadow_style=”preset3″ box_shadow_blur=”0px” box_shadow_color=”rgba(0,0,0,0)” locked=”off” global_colors_info=”{}” text_line_height__hover=”1.7em” text_line_height__hover_enabled=”1.7em” box_shadow_blur__hover=”38px” box_shadow_blur__hover_enabled=”on” box_shadow_color__hover=”rgba(34,42,137,0.09)” box_shadow_color__hover_enabled=”on” text_font_size__hover=”14px” text_font_size__hover_enabled=”14px” text_letter_spacing__hover=”0px” text_letter_spacing__hover_enabled=”0px” text_text_shadow_color__hover=”rgba(0,0,0,0.4)” text_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” link_font_size__hover=”14px” link_font_size__hover_enabled=”14px” link_letter_spacing__hover=”0px” link_letter_spacing__hover_enabled=”0px” link_line_height__hover=”1em” link_line_height__hover_enabled=”1em” link_text_shadow_color__hover=”rgba(0,0,0,0.4)” link_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” ul_font_size__hover=”14px” ul_font_size__hover_enabled=”14px” ul_letter_spacing__hover=”0px” ul_letter_spacing__hover_enabled=”0px” ul_line_height__hover=”1em” ul_line_height__hover_enabled=”1em” ul_text_shadow_color__hover=”rgba(0,0,0,0.4)” ul_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” ol_font_size__hover=”14px” ol_font_size__hover_enabled=”14px” ol_letter_spacing__hover=”0px” ol_letter_spacing__hover_enabled=”0px” ol_line_height__hover=”1em” ol_line_height__hover_enabled=”1em” ol_text_shadow_color__hover=”rgba(0,0,0,0.4)” ol_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” quote_font_size__hover=”14px” quote_font_size__hover_enabled=”14px” quote_letter_spacing__hover=”0px” quote_letter_spacing__hover_enabled=”0px” quote_line_height__hover=”1em” quote_line_height__hover_enabled=”1em” quote_text_shadow_color__hover=”rgba(0,0,0,0.4)” quote_text_shadow_color__hover_enabled=”rgba(0,0,0,0.4)” background_layout__hover=”light” background_layout__hover_enabled=”light”]<\/p>\n
Production finished product<\/h4>\n
- \n
- Produits dentaires SA<\/li>\n
- Mediplant
- Universit\u00e9 de Gen\u00e8ve https:\/\/ispso.unige.ch\/ispso\/index.php<\/a><\/li>\n<\/ul>\n
- Rosell-Lallemand https:\/\/www.lallemandpharma.com<\/a><\/li>\n<\/ul>\n
- Produits dentaires SA<\/li>\n
- Mediplant
- Values: 2 to 3 values to be discussed together.<\/li>\n<\/ul>\n
- Mission: To bring the first product to market within 3 years with a solid proof of concept.<\/li>\n<\/ul>\n
- Sister company of PHARMALP SA used to create an opportunity to leverage a patent by investing in the development of a pharmaceutical product<\/li>\n<\/ul>\n
- Founded in 2021 by 4 co-founders with solid experience in the pharmaceutical industry.<\/li>\n<\/ul>\n
- IBEX Therapeutics, a Swiss company specialised in therapies based on biological products derived from plant extracts.<\/li>\n<\/ul>\n
- Mission: To bring the first product to market within 3 years with a solid proof of concept.<\/li>\n<\/ul>\n
- Sister company of PHARMALP SA used to create an opportunity to leverage a patent by investing in the development of a pharmaceutical product<\/li>\n<\/ul>\n
- Founded in 2021 by 4 co-founders with solid experience in the pharmaceutical industry.<\/li>\n<\/ul>\n
- IBEX Therapeutics, a Swiss company specialised in therapies based on biological products derived from plant extracts.<\/li>\n<\/ul>\n
- Oral candidiasis, 51-year-old female, after the 18th fraction of radiotherapy in the OPC group. Whitish pseudomembranes and drops (arrows) are observed on the hard palate, which is devoid of mucositis (A). (A). Mucositis grade 2 to 3, 57-year-old male, after the 25th fraction of radiotherapy in the non-OPC group. Whitish pseudomembranes and drops (arrows) are observed on the hard palate, which is devoid of mucositis (A). (B). (OPC: oropharyngeal candidiasis)<\/em><\/li>\n<\/ul>\n
- (Upper image) Large ulceration of the lower labial mucosa of a patient receiving deforolimus (AP23573) is shown. The borders were irregular. Although the ulcer was not penetrating, it was extremely painful. The clinical appearance was identical to that of major aphthous stomatitis.<\/em><\/li>\n<\/ul>\n
- (Upper image) Large ulceration of the lower labial mucosa of a patient receiving deforolimus (AP23573) is shown. The borders were irregular. Although the ulcer was not penetrating, it was extremely painful. The clinical appearance was identical to that of major aphthous stomatitis.<\/em><\/li>\n<\/ul>\n
- (Pictures 2 & 3 – esophagus) – Qiu WZ et al. A retrospective study of 606 cases of nasopharyngeal carcinoma with or without oropharyngeal candidiasis during radiotherapy. PLOS one 2017<\/em><\/li>\n<\/ul>\n
- (Picture 1 – mouth) – Sonis S et al. Preliminary characterization of oral lesions associated with inhibitors of mammalian target of rapamycin in cancer patients. Cancer 2010<\/em><\/li>\n<\/ul>\n
- Oral candidiasis, 51-year-old female, after the 18th fraction of radiotherapy in the OPC group. Whitish pseudomembranes and drops (arrows) are observed on the hard palate, which is devoid of mucositis (A). (A). Mucositis grade 2 to 3, 57-year-old male, after the 25th fraction of radiotherapy in the non-OPC group. Whitish pseudomembranes and drops (arrows) are observed on the hard palate, which is devoid of mucositis (A). (B). (OPC: oropharyngeal candidiasis)<\/em><\/li>\n<\/ul>\n
- (Upper image) Large ulceration of the lower labial mucosa of a patient receiving deforolimus (AP23573) is shown. The borders were irregular. Although the ulcer was not penetrating, it was extremely painful. The clinical appearance was identical to that of major aphthous stomatitis.<\/em><\/li>\n<\/ul>\n